Fluticasone / salmeterol (Advair, Wixela) — 2026 Medicare Part D coverage
fluticasone / salmeterol — sold as Advair, Wixela: 18 forms appear in Medicare Part D formularies for 2026. This page reports what plans filed with CMS; it does not recommend a plan.
Which plans in your county cover fluticasone / salmeterol?
Pick a county to see every Medicare Advantage plan filed there and every stand-alone Part D plan in its region, with this drug's tier, restrictions and tier cost sharing.
How to read drug coverage
Tier is the cost-sharing tier the plan assigned the drug in its CMS formulary filing; lower tiers usually cost less. PA = prior authorization, ST = step therapy (try another drug first), QL = quantity limit. Not on formulary means the plan did not list this exact form; the plan may cover another strength or a formulary exception may be possible. Cost sharing is the plan's initial-coverage amount for the tier as filed with CMS; the deductible, the $2,100 annual out-of-pocket cap, the $35 insulin cap and negotiated prices for selected drugs can change what you actually pay. Formularies change during the year; the plan's formulary document and Medicare.gov govern.
What the star rating under each Medicare Advantage plan means
What the star rating means. CMS rates every Medicare Advantage contract (the "H" number in the plan ID — all plans under it share the rating) on a 1-to-5 scale each October, from about 40 measures of care quality, member experience, complaints and appeals, customer service and, for plans with drug coverage, drug safety and pricing. The 2026 rating is largely based on performance measured in 2024.
5 Excellent4 Above average3 Average2 Below average1 Poor
Not rated means CMS published no overall rating — usually a contract too new to be measured or with too few members ("not enough data"); it is not a low score. A 5-star contract can be joined outside the normal enrollment windows (the 5-star Special Enrollment Period, Dec 8 – Nov 30). Medicare.gov flags contracts rated below 3 stars for three years running as low-performing. Stars describe the contract's past performance as CMS measured it; they are not a recommendation, and they do not tell you whether a plan's network, drugs or costs fit you.
Forms and strengths in 2026 formularies
| Form | Formularies listing it | Most common tier | PA | ST | QL |
|---|---|---|---|---|---|
| fluticasone propionate/salmeterol 100/50 MCG/INHAL Dry Powder Inhaler, 60 Blisters generic · RxCUI 896184 | 313 (95%) | 2 | 0 | 1 | 305 |
| fluticasone propionate/salmeterol 250/50 MCG/INHAL Dry Powder Inhaler, 60 Blisters generic · RxCUI 896209 | 313 (95%) | 2 | 0 | 1 | 305 |
| fluticasone propionate/salmeterol 500/50 MCG/INHAL Dry Powder Inhaler, 60 Blisters generic · RxCUI 896228 | 313 (95%) | 2 | 0 | 1 | 305 |
| Wixela Inhub 100/50 MCG/INHAL Dry Powder Inhaler, 60 Actuations brand · RxCUI 2110510 | 307 (94%) | 2 | 0 | 1 | 298 |
| Wixela Inhub 250/50 MCG/INHAL Dry Powder Inhaler, 60 Actuations brand · RxCUI 2110513 | 307 (94%) | 2 | 0 | 1 | 298 |
| Wixela Inhub 500/50 MCG/INHAL Dry Powder Inhaler, 60 Actuations brand · RxCUI 2110516 | 307 (94%) | 2 | 0 | 1 | 298 |
| ADVAIR HFA 115/21 MCG/INHAL Metered Dose Inhaler, 120 Actuations brand · RxCUI 896245 | 281 (86%) | 3 | 0 | 1 | 277 |
| ADVAIR HFA 230/21 MCG/INHAL Metered Dose Inhaler, 120 Actuations brand · RxCUI 896273 | 281 (86%) | 3 | 0 | 1 | 277 |
| ADVAIR HFA 45/21 MCG/INHAL Metered Dose Inhaler, 120 Actuations brand · RxCUI 896237 | 281 (86%) | 3 | 0 | 1 | 277 |
| fluticasone propionate/salmeterol 113/14 MCG/INHAL Dry Powder Inhaler, 60 Actuations generic · RxCUI 1918194 | 101 (31%) | 3 | 0 | 0 | 90 |
| fluticasone propionate/salmeterol 232/14 MCG/INHAL Dry Powder Inhaler, 60 Actuations generic · RxCUI 1918203 | 101 (31%) | 3 | 0 | 0 | 90 |
| fluticasone propionate/salmeterol 55/14 MCG/INHAL Dry Powder Inhaler, 60 Actuations generic · RxCUI 1918209 | 101 (31%) | 3 | 0 | 0 | 90 |
| fluticasone propionate/salmeterol 115/21 MCG/INHAL Metered Dose Inhaler, 120 Actuations generic · RxCUI 896244 | 30 (9%) | 1 | 0 | 0 | 21 |
| fluticasone propionate/salmeterol 230/21 MCG/INHAL Metered Dose Inhaler, 120 Actuations generic · RxCUI 896272 | 30 (9%) | 1 | 0 | 0 | 21 |
| fluticasone propionate/salmeterol 45/21 MCG/INHAL Metered Dose Inhaler, 120 Actuations generic · RxCUI 896236 | 30 (9%) | 1 | 0 | 0 | 21 |
| ADVAIR DISKUS 100/50 MCG/INHAL Dry Powder Inhaler, 60 Blisters brand · RxCUI 896185 | 5 (2%) | 3 | 0 | 0 | 5 |
| ADVAIR DISKUS 250/50 MCG/INHAL Dry Powder Inhaler, 60 Blisters brand · RxCUI 896212 | 5 (2%) | 3 | 0 | 0 | 5 |
| ADVAIR DISKUS 500/50 MCG/INHAL Dry Powder Inhaler, 60 Blisters brand · RxCUI 896229 | 5 (2%) | 3 | 0 | 0 | 5 |
Counts are formularies (of 328) in the CMS file that list the form, and how many of those apply prior authorization (PA), step therapy (ST) or a quantity limit (QL). Many plans share one formulary, so plan counts in a county will differ.
How to read drug coverage
Tier is the cost-sharing tier the plan assigned the drug in its CMS formulary filing; lower tiers usually cost less. PA = prior authorization, ST = step therapy (try another drug first), QL = quantity limit. Not on formulary means the plan did not list this exact form; the plan may cover another strength or a formulary exception may be possible. Cost sharing is the plan's initial-coverage amount for the tier as filed with CMS; the deductible, the $2,100 annual out-of-pocket cap, the $35 insulin cap and negotiated prices for selected drugs can change what you actually pay. Formularies change during the year; the plan's formulary document and Medicare.gov govern.
What the star rating under each Medicare Advantage plan means
What the star rating means. CMS rates every Medicare Advantage contract (the "H" number in the plan ID — all plans under it share the rating) on a 1-to-5 scale each October, from about 40 measures of care quality, member experience, complaints and appeals, customer service and, for plans with drug coverage, drug safety and pricing. The 2026 rating is largely based on performance measured in 2024.
5 Excellent4 Above average3 Average2 Below average1 Poor
Not rated means CMS published no overall rating — usually a contract too new to be measured or with too few members ("not enough data"); it is not a low score. A 5-star contract can be joined outside the normal enrollment windows (the 5-star Special Enrollment Period, Dec 8 – Nov 30). Medicare.gov flags contracts rated below 3 stars for three years running as low-performing. Stars describe the contract's past performance as CMS measured it; they are not a recommendation, and they do not tell you whether a plan's network, drugs or costs fit you.